Build up your business to your very own customization starting with the property. Lease New Madrid (MO) undeveloped land as a foundation to build on or use for other purposes like agriculture. Whatever your New Madrid (MO) business venture is, you will need to acquire the proper clearance, permits and ensure your type of business is compatible with New Madrid (MO) local and regional zoning by-laws and city ordinances as such. Consult legal advice before signing any contracts.